101 - Document - Document and Entity Information
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103 - Statement - Consolidated Balance Sheets
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104 - Statement - Consolidated Balance Sheets (Parenthetical)
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105 - Statement - Consolidated Statements of Operations and Comprehensive Loss
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106 - Statement - Consolidated Statements of Cash Flows
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107 - Disclosure - Nature of the Business and Basis of Presentation
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108 - Disclosure - Summary of Significant Accounting Policies
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109 - Disclosure - Accrued Expenses
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110 - Disclosure - Notes Payable
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111 - Disclosure - Stockholders' Equity
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112 - Disclosure - Stock-Based Awards
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113 - Disclosure - Commitments and Contingencies
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114 - Disclosure - Retirement Plan
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115 - Disclosure - Australia Research and Development Tax Incentive
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116 - Disclosure - Nature of the Business and Basis of Presentation (Policies)
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117 - Disclosure - Summary of Significant Accounting Policies (Tables)
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118 - Disclosure - Accrued Expenses (Tables)
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119 - Disclosure - Notes Payable (Tables)
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120 - Disclosure - Stock-Based Awards (Tables)
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121 - Disclosure - Commitments and Contingencies (Tables)
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122 - Disclosure - Nature of the Business and Basis of Presentation - Additional Information (Detail)
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123 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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124 - Disclosure - Summary of Significant Accounting Policies - Summary of Common Stock Equivalents Outstanding (Detail)
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125 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Detail)
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126 - Disclosure - Notes Payable - Additional Information (Detail)
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127 - Disclosure - Notes Payable - Schedule of Estimated Future Principal Payments Due under Term Loan (Detail)
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128 - Disclosure - Stockholders' Equity - Additional Information (Detail)
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129 - Disclosure - Stock-Based Awards - Additional Information (Detail)
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130 - Disclosure - Stock-Based Awards - Summary of Stock-Based Compensation Expense Related to Stock Options and Restricted Common Stock (Detail)
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131 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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132 - Disclosure - Commitments and Contingencies - Schedule of Future Minimum Lease Payments for Operating Leases (Detail)
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133 - Disclosure - Retirement Plan - Additional Information (Detail)
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134 - Disclosure - Australia Research and Development Tax Incentive - Additional Information (Detail)
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